Direct MicroRNA Sequencing using Nanopore Induced Phase-Shift Sequencing (NIPSS)
نویسندگان
چکیده
منابع مشابه
Nanopore Sequencing: A Survey
A single molecule of Deoxyribonucleic acid (DNA) is being sequenced by using an innovative concept of Nanopore. The orientation of nanopore define the channel of ions through the pore comes into contact with nucleotide, the permutation and the transition kinematics of each molecule of DNA. The divergence of electrical signal observed when the four chemical bases adenine (A), guanine (G), cytosi...
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Received 6 January 2015; accepted 5 November 2015; published online 6 May 2016; doi:10.1038/nbt.3423 and together with Sergey Bezrukov at the US National Institutes of Health (NIH), had established the conditions that were necessary to avoid spontaneous gating (pore closure) of the a-hemolysin channel3. This was important, because spontaneous gating would have hindered, or confused, observation...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2020
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2019.11.2638